Tregs

October 25, 2017October 26, 2017

#MSParis2017 – Researchers Suggest Propionic Acid Could Be Used as Add-on Treatment in MS

News

Propionic acid supplements alter the composition and behavior of immune cells in multiple sclerosis (MS) patients — likely by changing the composition of gut bacteria, according ... Read more

October 10, 2017October 11, 2017

Researchers Identify Quality Control Regulatory Cells That Prevent the Production of Autoantibodies

News

The discovery of an immune cell quality control mission may have put scientists a step closer to understanding how autoimmune conditions such as multiple sclerosis arise. University ... Read more

September 25, 2017September 25, 2017

MS Gene Therapy Shows Good Results in Mice, but Human Trials Remain Distant

News

Researchers have taken the first steps towards the development of a gene therapy for multiple sclerosis — a treatment that boosted anti-inflammatory immune processes and reversed ... Read more

September 14, 2017September 14, 2017

Specific Gut Bacteria May Drive Progression of Multiple Sclerosis, Study Finds

News

Specific gut bacteria may drive the progression of multiple sclerosis, according to a study showing that two bacterial species made the disease worse in a mouse ... Read more

July 25, 2017July 27, 2017

Lilly, Nektar Partner to Develop T-Cell Stimulator NKTR-358 for MS, Autoimmune Disorders

News

Eli Lilly and Nektar Therapeutics have established a development and commercial agreement for the investigational T-cell stimulator therapy NKTR-358 for the treatment of autoimmune disorders, including ... Read more

April 6, 2017April 6, 2017

Nektar Therapeutics Starts Phase 1 Trial of NKTR-358 for Autoimmune Diseases

News

Nektar Therapeutics has started a Phase 1 clinical trial of its biologic therapy NKTR-358 for inflammatory disorders and autoimmune diseases like multiple sclerosis. NKTR-358 is a first-in-class regulatory ... Read more

February 24, 2017February 24, 2017

#ACTRIMS2017 – Some Fatty Acids in Diet Help, Others Hurt Immune System, Study Reports

News

Short-chain dietary fatty acids, such as propionate, drive the production of regulatory immune T-cells in patients with multiple sclerosis (MS), while long-chain acids promote T-cells that ... Read more

January 24, 2017January 24, 2017

University of Maryland and VA to Investigate Tregs as Possible MS Treatment

News

The VA Maryland Health Care System (VAMHCS) and the University of Maryland Fischell Department of Bioengineering are collaborating in a research initiative that aims to increase our understanding ... Read more

November 3, 2016November 3, 2016

Myelin May Hold Raw Material for Immunizing MS Patients Against Demyelination

News

Immunization with molecules present specifically in myelin may be a new approach to treating multiple sclerosis (MS), according to a recent study that found that the ... Read more

October 21, 2016October 31, 2016

Umbilical Cord Stem Cells Work to Restore Immune System Balance in Early Study

News

Damaging immune system defects seen in patients with multiple sclerosis (MS) can be repaired using a simple stem cell approach, according to a new study by researchers in ... Read more

September 15, 2016September 15, 2016

#ECTRIMS2016 – Immune Cells Linked to Autoimmunity Found in MS Patients’ Gut

News

Immune cells, believed to drive autoimmunity, are selectively increased in the gut of patients with multiple sclerosis (MS), along with lower numbers of cells controlling inflammation, ... Read more

April 1, 2016April 5, 2016

MS Therapy Tecfidera Might Exert its Actions by Increasing Specific B-cells

News

Editor’s note: The term B-cells is, in fact, a collective term for a group of cells having rather different properties. Some B-cells cells play a role ... Read more

February 4, 2016February 4, 2016

RRMS Drug Works by Shifting Anti-Inflammatory Immune Profile, Study Shows

News

Researchers have found that changes in the composition of immune molecules — specifically, a shift to more anti-inflammatory cytokines and regulatory T-cells (Tregs) — likely account for ... Read more

December 1, 2015December 1, 2015

Multiple Sclerosis-like Disorder Blocked in Mice Study

News

Researchers demonstrated a process that prevented an induced autoimmune disease from taking hold in the central nervous system of mice, and think it has the potential of ... Read more

December 1, 2015December 1, 2015

National Multiple Sclerosis Society Awards Wisconsin Researcher With Grant To Fuel Promising Study

News

The National Multiple Sclerosis Society awarded a $700,000 research grant to Dr. Bonnie Dittel, Senior Investigator at BloodCenter of Wisconsin (BCW) and adjunct professor at the Medical ... Read more

November 24, 2015November 24, 2015

MS Patients on Salt-heavy Diets Risk Inflammation

News

Findings from two studies, recently published in the Journal of Clinical Investigation, indicate that high levels of salt alter the stability of the immune system and make ... Read more