Inflammation

January 9, 2018January 9, 2018

Cholesterol Buildup Limits Regeneration of Nerve-cell-protecting Sheath, Study Shows

News

The nerve-cell-protecting myelin sheath’s failure to remove cholesterol after the membrane has been damaged limits its ability to regenerate, German researchers report. Their finding has important ... Read more

December 14, 2017December 14, 2017

Body’s Biological Clock and Time of Day Affects Immune Cells, Mouse Study Shows

News

Researchers further explored how our internal biological clock — known as circadian rhythm — influences immune system responses. Disruptions to that rhythm are associated with immune diseases ... Read more

November 27, 2017November 27, 2017

Vegetable-rich Diet Promotes Bacteria That Fights Inflammation in MS, Study Shows

News

A diet rich in vegetables and low in protein reduced inflammation in multiple sclerosis (MS) patients by modulating the gut microbiome and promoting bacteria that helps ... Read more

November 8, 2017November 8, 2017

Blocking CXCR7 Receptor of Mature Monocytes Could Be New Therapeutic Strategy in MS

News

The CXCR7 receptor present on mature monocytes — a type of white blood cell — may be a therapeutic target to alleviate the inflammation seen in multiple ... Read more

October 31, 2017October 31, 2017

#MSParis2017 – T-cell vs. B-cell Debate More Meeting of Minds Than ‘Rumble in the Jungle’

News

News commentary One particular session on Day 2 of the four-day 7th Joint ECTRIMS-ACTRIMS Meeting — which drew 10,000 researchers, doctors, industry representatives, and patient advocates ... Read more

October 24, 2017October 25, 2017

Two Studies Show IL-35 Protein’s Potential to Curb Inflammation in Autoimmune Diseases

News

An immune signaling protein called interleukin-35 has anti-inflammatory properties that scientists might harness to develop a therapy for multiple sclerosis and other autoimmune disorders, according to ... Read more

September 28, 2017September 28, 2017

MS Alphabet: Interferon, INO, inflammation and Other ‘I’ Terms

Columns, MS in Moderation, a column by Tamara Sellman

(Editor’s note: Tamara Sellman continues her occasional series on the MS alphabet with this column about terms starting with the letter I.) Symptoms of MS Incontinence ... Read more

September 15, 2017September 18, 2017

Probiotics Consumption May Improve Certain Disease Parameters in MS Patients, Study Suggests

News

Probiotics may improve the health of people with multiple sclerosis (MS) by reducing disability and improving inflammatory and metabolic parameters, an Iranian study shows. Live microorganisms linked ... Read more

September 14, 2017September 14, 2017

Specific Gut Bacteria May Drive Progression of Multiple Sclerosis, Study Finds

News

Specific gut bacteria may drive the progression of multiple sclerosis, according to a study showing that two bacterial species made the disease worse in a mouse ... Read more

August 30, 2017August 30, 2017

Retroviral RRMS Treatment GNbAC1 Fails Phase 2 Trial, But Research Continues, Say Sponsors

News

A Phase 2b trial assessing the experimental retroviral-targeting treatment GNbAC1 in patients with relapsing-remitting multiple sclerosis (RRMS) failed to meet its primary goal of reducing brain lesions ... Read more

August 25, 2017September 4, 2017

Omega-3 Fatty Acids May Reduce Inflammation by Changing Immune Cell Processes, Study Suggests

News

Omega-3 fatty acids might reduce inflammatory processes by boosting a mechanism that cleans out dysfunctional or unnecessary proteins in a certain type of immune cells, according ... Read more

August 23, 2017August 24, 2017

Researchers Identify Nerve Pathway Linking Brain Inflammation, Gut Dysfunction in MS

News

Chronic stress and inflammation in the brain can cause multi-organ dysfunction including severe gut failure, mediated by a newly identified nerve pathway in animal models of ... Read more

August 14, 2017August 15, 2017

Human Gut Microbes May Help Suppress MS, New Research Suggests

News

A bacteria present in the gut, called Prevotella histicola, prevented multiple sclerosis from developing in a preclinical mouse model, found researchers at the Mayo Clinic in ... Read more

July 24, 2017July 25, 2017

Pre-Existing Inflammatory Diseases Reduce Therapeutic Potential of Stem Cells for MS Treatment, Study Shows

News

According to a study by researchers at Cleveland’s Case Western Reserve University School of Medicine, pre-existing inflammatory diseases affecting the central nervous system make mesenchymal stem ... Read more

July 12, 2017July 13, 2017

Antidepressant Luvox Promotes Production of Neuron-protecting Sheath in Rats, Study Shows

News

A new study on rats indicates that the antidepressant Luvox promotes the production of the neuron-protecting coating that is deficient in multiple sclerosis. It also significantly ... Read more

July 7, 2017July 11, 2017

FOXP3 Gene Mutations May Explain Immune System Excitability in MS and Other Diseases

News

A gene mutation may explain the uncontrolled, inflammatory immune response seen in autoimmune and chronic inflammatory diseases like multiple sclerosis, scientists at the Research Institute of ... Read more

June 9, 2017June 9, 2017

New Way of Growing Astrocytes from Stem Cells May Aid Research into Brain Disorders Like MS

News

Researchers at The Salk Institute have developed a way to grow vital brain cells called astrocytes from stem cells, a potential breakthrough for basic and clinical research into ... Read more

May 4, 2017May 4, 2017

Cytomegalovirus Infection Worsens Multiple Sclerosis, Study in Mice Shows

News

A cytomegalovirus infection triggers an increase in inflammatory and cytotoxic immune cells in mice with multiple sclerosis (MS), which leads to enhanced inflammation and loss of nerve-protecting ... Read more

May 2, 2017May 2, 2017

Two Proteins Play Key Roles in Regulating Brain Inflammation, MS-related Study Shows

News

Neuroinflammation is an essential process in the development and progression of several neurodegenerative diseases, including multiple sclerosis (MS), Alzheimer’s and Parkinson’s. Researchers from the University of ... Read more

April 24, 2017April 23, 2017

Hypothyroidism and What It Shares with MS

Columns, Faith of the Mustard Seed - a Column by Debi Wilson

In 2004, I was diagnosed with hypothyroidism, a condition in which the thyroid is underactive and doesn’t product enough important hormones. Six years later, I was diagnosed ... Read more

February 23, 2017February 23, 2017

Brazil Allows HempMeds to Import RSHO Cannabidiol for MS Treatment

News

The Brazilian government has authorized HempMeds Brasil, a unit of California-based Medical Marijuana, to import the parent company’s hemp cannabidiol (CBD) oil flagship product — known as Real Scientific ... Read more

February 9, 2017February 9, 2017

Component of Traditional Medicinal Herb Improves Symptoms in MS Mouse Model, Study Shows

News

Paeoniflorin (PF), a herb component used in Chinese medicine, improved symptoms and reduced inflammation in a mouse model that recapitulates the human features of multiple sclerosis ... Read more

February 6, 2017February 6, 2017

Researchers Identify Gene Regions with High Levels of Proteins Linked to MS

News

A genome-wide study has identified DNA regions associated with higher levels of circulating cytokines, small proteins that pay a role in inflammatory diseases such as multiple sclerosis ... Read more

January 27, 2017January 27, 2017

Tiny Molecules in Blood Could Be Biomarkers of MS Progression, Study Says

News

MicroRNAs in the blood could serve as biomarkers to monitor the progression of multiple sclerosis (MS), as well as help identify which mechanisms are at play ... Read more

January 17, 2017January 17, 2017

Tecfidera Seen to Potentially Limit Vision Problems in MS

News

Genetically silencing the transcription factor Nrf2 in a mouse model of multiple sclerosis (MS) results in visual deficits, inflammation of the optic nerve, and degeneration of ... Read more

January 5, 2017January 5, 2017

CHANGE-MS Phase 2 Study Fully Enrolled Early, Results Due in Fall

News

GeNeuro recently announced that it has finished enrolling multiple sclerosis (MS) patients in the CHANGE-MS Phase 2b  study — several months ahead of schedule. The company now expects to ... Read more

December 12, 2016December 12, 2016

3-D Structure of CCR2 Receptor, While Bound to Its Inhibitors, Captured for 1st Time

News

Scientists unraveled the 3-D structure of a key receptor linked to inflammation in multiple sclerosis (MS) — the CC chemokine receptor 2 (CCR2) receptor — when ... Read more

December 8, 2016December 8, 2016

MS Patients in Clinical Trial of GNbAC1 May Continue with Therapy in Extension Study

News

Multiple sclerosis (MS) patients now taking part in a Phase 2b clinical trial testing the efficacy and safety of the antibody GNbAC1 will be invited to continue with treatment for ... Read more

November 22, 2016November 22, 2016

Australian Researcher Honored for Discovery That May Lead to Anti-Inflammatory Therapy

News

Dr. Rebecca Coll, a young researcher at the University of Queensland Institute of Molecular Bioscience, won the 2016 Research Australia Discovery Award for her work in identifying promising anti-inflammatory ... Read more

November 15, 2016November 15, 2016

New Way of Scanning Brain Captures Onset of Inflammation in MS Mice and Patients

News

Advances in brain imaging are making it possible to visualize early and ongoing events in multiple sclerosis (MS) — beginning with the first signs of inflammation caused ... Read more

November 4, 2016November 4, 2016

NIH Researcher Working on MS Imaging Wins 2016 Barancik Prize for Innovation

News

Dr. Daniel Reich, a researcher with the National Institutes of Health (NIH),  has been recognized for his pioneering work on brain imaging to advance both the treatment of ... Read more

September 16, 2016September 16, 2016

#ECTRIMS2016 – Inflammatory Profiles of Brain Seen to Predict MS Disability

News

Immune activity in brain membranes may be the key to determining inflammatory profiles in the brain. These profiles, in turn, are linked to levels of brain ... Read more

September 15, 2016September 15, 2016

#ECTRIMS2016 – Immune Cells Linked to Autoimmunity Found in MS Patients’ Gut

News

Immune cells, believed to drive autoimmunity, are selectively increased in the gut of patients with multiple sclerosis (MS), along with lower numbers of cells controlling inflammation, ... Read more

August 10, 2016August 10, 2016

Brain Inflammation Countered by Neuronal Growth in Mouse Model of MS

News

As inflammation and neuronal death progressed in the brains of mice with multiple sclerosis (MS), a molecular signaling pathway with a key player called Wnt was ... Read more

July 15, 2016July 15, 2016

Gut Microbiome in MS Patients Seen to Favor Inflammatory Bacteria in Study

News

A link indeed appears to exist between multiple sclerosis (MS) and unusual changes in the bacterial composition of the gut, according to researchers at Brigham and Women’s Hospital (BWH). ... Read more

July 12, 2016July 12, 2016

High Depression Rates in MS Patients Tied to Brain Inflammation in Recent Study

News

Inflammation in a brain region called the hippocampus might explain why patients with multiple sclerosis (MS) suffer from depression far more often than patients with other ... Read more

June 1, 2016June 1, 2016

MS Research Australia Supporting Effort to Harness Anti-inflammatory Potential of Parasitic Worms

News

Researchers at the University of Technology Sydney (UTS) ithree institute are taking a novel approach in an attempt to halt disease progression in multiple sclerosis (MS). The scientists are planning to ... Read more

May 18, 2016May 18, 2016

Gut Microbiota in Young MS Patients Is Higher in Pro-Inflammatory Bacteria Than Usual, Study Finds

News

Children and adolescents with multiple sclerosis (MS) differ from others in the composition of their gut flora, with higher levels of inflammation-causing bacteria and lower levels of anti-inflammatory bacteria, according ... Read more

May 11, 2016May 11, 2016

Diet Plays a Role in MS Progression Through Its Impact on Astrocytes, Researchers Say

News

Dietary habits and the composition of the gut flora can influence neuroinflammation and affect the outcome of neurodegenerative diseases such as multiple sclerosis (MS), according to a study ... Read more

April 26, 2016April 26, 2016

Cytokine Once Thought Only to Promote Inflammation Now Seen to Have Restorative Properties, Too

News

Researchers at the School of Medicine of the University of California (UC), Riverside, found that TNF-alpha, a factor known for its pro-inflammatory actions, also triggers processes ... Read more