Using Balloons to Increase Blood Flow from Brain Fails to Help MS Patients, Trial Finds

Using Balloons to Increase Blood Flow from Brain Fails to Help MS Patients, Trial Finds

The Brave Dreams trial (NCT01371760) involved 115 people between 18 and 65 years old with relapsing-remitting multiple sclerosis, or RRMS. Conducted at six MS centers, the trial’s main goal was to see if angioplasty would increase blood flow from patients’ brains and spinal cords.

Doctors performed angioplasty on 76 patients. Thirty-nine patients served as a control group, with doctors inserting a catheter in their blood vessels, but no balloon.

Researchers followed the two groups for 12 months. They performed MRI scans on the patients at six and 12 months to check for new or enlarged brain lesions.

No serious adverse events occurred with either procedure, researchers said.

Doctors were able to restore blood flow in 54 percent of the angioplasty group, but it failed to improve their functioning. The two groups had similar measures of balance, dexterity, vision, and ability to walk. There were also no differences in the amount of urine left in patients’ bladder after they had urinated.

The percentage of angioplasty patients who failed to develop new brain lesions was higher than in the control group, but the difference was small. Researchers called for more studies on the matter.


  1. Rosanne Costain says:

    I was part of this study locally. It did not cure my MS, what it did was reduce the sensitivity in my hands and legs, cleared a lot of my “brain fog” stopped my slurring of words and improved my balance.
    What I wish I could get is venaplasty on the other side.
    I was happy to be involved with this study, as I was with other studies that produced no results.
    I have now “aged out” of volunteering for other studies otherwise I wouild be very glad to do so.

    • Per West says:

      Of course it works. Why should MS-patients be the only ones who’s not responding positive to a healthy bloodflow.
      Only corruptive neurologists can claim, that this is not the case.
      One year they claimed, that the lympnodes was not present in our brain.
      It is obvious, that they do not know anything about MS, other that there is plenty of money to collect by not trying to learn about the disease.

  2. Edward Robak says:

    I had my CCSVI treatment in Poland in 2010. My fatigue, balance and autonomic functions improved greatly and have stayed improved. However, unlike most patients, I had a stent implanted. I believe that the stenoses in most people who only had ballooning done snapped back into place. That doesn’t mean that CCSVI treatment doesn’t work, it means that, for those people that could benefit from it, using stents should be considered.

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